Guidelines for Acromegaly Management: An Update
نویسندگان
چکیده
منابع مشابه
Pegvisomant in acromegaly: an update
BACKGROUND In 2007, we published an opinion document to review the role of pegvisomant (PEG) in the treatment of acromegaly. Since then, new evidence emerged on the biochemical and clinical effects of PEG and on its long-term efficacy and safety. AIM We here reviewed the emerging aspects of the use of PEG in clinical practice in the light of the most recent literature. RESULTS The clinical ...
متن کاملGuidelines for the management of contact dermatitis: an update.
These guidelines for management of contact dermatitis have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence-based guidance for investigation and treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, including details of relevant epidemiological aspects, diagnosis and invest...
متن کاملCurrent treatment guidelines for acromegaly.
Acromegaly, an indolent disorder of growth hormone (GH) hypersecretion is most typically caused by a somatotroph cell adenoma and may be treated by several modalities. Transsphenoidal surgical resection of micro-adenomas by experienced neurosurgeons results in biochemical normalization (postglucose GH <2 ng/mL, assay-dependent, age- and sex-matched IGF-I levels) in 70% of patients. However, ove...
متن کاملUpdate on Acromegaly
In addition to the classic somatic changes in acromegaly such as enlargement of the hands and feet (Figure 1), this disorder is associated with significant medical comorbidities including sleep apnea, hypertension, Type II diabetes, and hypertrophic cardiomyopathy. Sleep apnea is found in over 50% of patients with acromegaly. All of these comorbidites improve with biochemical control of the dis...
متن کاملDiagnosis and Management of Acromegaly in 2014 ( Update from 2012 )
Acromegaly is an uncommon disorder that, in the vast majority of cases, is the result of a growth hormone (GH)-secreting pituitary adenoma. Because tumors are often macroadenomas at the time of diagnosis, there may be a number of signs and symptoms related to local mass effects, including headache, visual field loss, ophthalmoplegia, and hypopituitarism. Chronic GH and insulin-like growth facto...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2009
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2008-2421